Your body’s ability to process nutrients, manage stress, and maintain long-term health depends heavily on a process called methylation. This panel looks at 10 key genetic variants (SNPs) that can impact how efficiently your body performs this process, along with lab tests that measure important nutrients that support it.

Methylation plays a role in mood, detox, energy production, and cardiovascular health. When this system is underperforming due to genetic factors or nutrient imbalances, it can lead to fatigue, brain fog, or increased health risks over time. PRYM Methyl+ helps you uncover your unique biology and gives you the insight to support your body more effectively.

Tests Performed
  • Genetic Markers: 10-SNP methylation panel
  • Metabolic: Homocysteine
  • Vitamin & Mineral Levels: Vitamin D, B12, Folate, Magnesium
Kit Includes
  • Easy to understand instructions
  • Collection device with tube
  • Heat pack
  • Bandages
  • Alcohol Swab
  • Prepaid return label and box
Collection Method
  • Blood
  • Swab

Test Details

Learn more about each test in this panel.

Genetic Markers

10-SNP Methylation Panel
This panel analyzes ten key SNPs (single nucleotide polymorphisms) involved in the methylation cycle—a process essential for detoxification, hormone regulation, neurotransmitter production, and DNA repair. Variants in genes like MTHFR, COMT, and others can affect how efficiently your body uses nutrients like B12 and folate, influencing energy, mood, inflammation, and long-term wellness.

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Homocysteine

Homocysteine
Homocysteine is a compound produced during methylation. Elevated levels can indicate issues in this pathway and may raise the risk of cardiovascular disease, cognitive decline, and chronic inflammation. Monitoring homocysteine is especially important if you have genetic variants affecting methylation.

Vitamin & Mineral Levels

Vitamin D
Essential for immune health, bone strength, and mood balance. Low levels are common in both men and women and can impact hormone levels, energy, and immune resilience.

Vitamin B12
Supports red blood cell formation, nerve function, and mental clarity. It also plays a vital role in methylation. Deficiency can lead to fatigue, brain fog, and mood changes—especially in those with MTHFR or other related variants.

Folate
A key player in methylation and DNA synthesis. Natural folate (not synthetic folic acid) is better utilized by people with MTHFR variants and supports cellular health, detox, and cardiovascular wellness.

Magnesium
An essential mineral involved in over 300 biochemical reactions, including methylation. It supports muscle recovery, sleep, energy production, and stress response—yet it’s one of the most commonly deficient nutrients in adults.

How the device works

Our FDA-cleared device makes collection quick and virtually painless.

Stick it on your arm, press a button, and in about five minutes, you’re done. No needle. No fuss.

Accessing your results

Once your sample reaches our lab, you’ll get your results in 2–3 business days. We’ll email you when they’re ready, and you can view them through your secure online portal.

Your report is easy to read and ready to share with your healthcare provider.

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